Who develops PAP?

Factor VII ManPulmonary alveolar proteinosis (PAP) is a very rare disease. The yearly prevalence (number of patients that are affected by the disease) in USA is 6.9 persons per million. In Japan, the yearly prevalence is similar (6.2/million). In Europe, however, the prevalence in the general population has not been investigated in large studies. But it is assumed to be the same as in USA (6-7/million).

Though PAP is a rare disease the typical PAP patient can be characterised by being:

  • Aged 25-50 at time of diagnosis
  • Male (men are 4 times more likely than women to be diagnosed with PAP)
  • Smoker (the disease seems to be more frequent in smokers)

Other PAP characteristics

If you have other diseases such as HIV or certain types of bone marrow cancer it increases your risk of developing PAP.

If you work in environments where you inhale mineral dust such as silica, titanium oxide, aluminum, and indium-tin oxide or insecticides, you may also be at increased risk of developing PAP.

Read more about what causes PAP here.

This website is sponsored by Savara Pharmaceuticals

Savara